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Adenosine 5'-diphosphate

Catalog No. T1723Cas No. 58-64-0
Alias ADP, adenosine pyrophosphate, Adenosine diphosphate

Adenosine 5'-diphosphate (ADP) is a naturally occurring nucleotide derived from the dephosphorylation of ATP. Adenosine 5'-diphosphate is essential for cellular metabolism and induces platelet aggregation.

Adenosine 5'-diphosphate

Adenosine 5'-diphosphate

Purity: 100%
Catalog No. T1723Alias ADP, adenosine pyrophosphate, Adenosine diphosphateCas No. 58-64-0
Adenosine 5'-diphosphate (ADP) is a naturally occurring nucleotide derived from the dephosphorylation of ATP. Adenosine 5'-diphosphate is essential for cellular metabolism and induces platelet aggregation.
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50 mg$30In Stock
100 mg$42In Stock
200 mg$58In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Adenosine 5'-diphosphate (ADP) is a naturally occurring nucleotide derived from the dephosphorylation of ATP. Adenosine 5'-diphosphate is essential for cellular metabolism and induces platelet aggregation.
In vitro
METHODS: Fibroblast-like synoviocytes FLS1 were treated with Adenosine 5'-diphosphate (100 µM) for 24 h, and gene expression levels were measured by RT-qPCR.
RESULTS: MCP-1/CCL-2 mRNA expression was up-regulated 2.31-fold in FLS1 cells treated with Adenosine 5'-diphosphate (100 µM). [1]
In vivo
METHODS: To investigate the role in tissue repair, Adenosine 5'-diphosphate (15.2 µg/kg) was applied topically to diabetic mice in a total excisional wound model once daily for 14 days.
RESULTS: Adenosine 5'-diphosphate accelerated cutaneous wound healing, improved new tissue formation, and increased collagen deposition and TGF-β production in the wounds.Adenosine 5'-diphosphate acts as a pro-absorptive mediator in diabetes-related cutaneous wounds. [2]
AliasADP, adenosine pyrophosphate, Adenosine diphosphate
Chemical Properties
Molecular Weight427.2
FormulaC10H15N5O10P2
Cas No.58-64-0
Storage & Solubility Information
Storagestore at low temperature,store under nitrogen,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 100 mg/mL (234.08 mM)
DMSO: 14 mM
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.3408 mL11.7041 mL23.4082 mL117.0412 mL
5 mM0.4682 mL2.3408 mL4.6816 mL23.4082 mL
10 mM0.2341 mL1.1704 mL2.3408 mL11.7041 mL
H2O
1mg5mg10mg50mg
20 mM0.1170 mL0.5852 mL1.1704 mL5.8521 mL
50 mM0.0468 mL0.2341 mL0.4682 mL2.3408 mL
100 mM0.0234 mL0.1170 mL0.2341 mL1.1704 mL

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